Artists from S-8ighty to Szpaku
- S-8ighty - Sad Frosty
- Sad Lovers & Giants - Saint Motel
- SaintDomGvng - Sam Cohen
- Sam Cooke - Sammi Smith
- Sammie - Sara Tavares
- Sarah - Sat
- Sat-B - Saya
- Saya & Dianke - Schoolly D
- Scientifik - Sean Garrett
- Sean Khan - Seedsmen to the World
- Seeker Lover Keeper - Sequence
- Ser Travis - Seum
- Seun Kuti - SHAED
- Shaëtan - Shannon Purser
- Shannon Shaw - She Wants Revenge
- Sheck Wes - Shinedown
- Shinee - Shuky & Aviva
- Shun Kaleyn - Sido La Dose
- Sidoine - Simba La Rue
- Simen Mitlid - Sinéad O'Connor
- Singuila - Six Million Dollar Weirdo
- Sixpence None The Richer - Skooly
- Skott - Slaughterhouse
- Slave - Slow Show
- Slowdive - Snakadaktal
- Snake - Social House
- Socks and Chimes - Soley Dancefloor
- Solillaquists of Sound - Sonny Alven
- Sonny Black - Sophie Rose
- Sophie Tapie - Soulsavers
- Soum Bill - Spartakus
- Special D - Sqeezer
- Squadra - Standard
- Standly - Static-x
- Status Quo - Stéphane Cadé
- Stephane Legar - Steve Brookstein
- Steve Earle - Stiltskin
- Stimulator Jones - Stray Kids
- Strayz Clan - Suga Free
- Sugababes - Sunset Boulevard
- Sunset Sons - Susan Tedeschi
- Susanna - Sweety
- Swenz - System Beat
- System Of A Down - Szpaku
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